DELIMITER $$
CREATE FUNCTION  `regex_replace`(pattern VARCHAR(1000),replacement VARCHAR(1000),original VARCHAR(1000))
 
RETURNS VARCHAR(1000)
DETERMINISTIC
BEGIN 
 DECLARE temp VARCHAR(1000); 
 DECLARE ch VARCHAR(1); 
 DECLARE i INT;
 SET i = 1;
 SET temp = '';
 IF original REGEXP pattern THEN 
  loop_label: LOOP 
   IF i>CHAR_LENGTH(original) THEN
    LEAVE loop_label;  
   END IF;
   SET ch = SUBSTRING(original,i,1);
   IF NOT ch REGEXP pattern THEN
    SET temp = CONCAT(temp,ch);
   ELSE
    SET temp = CONCAT(temp,replacement);
   END IF;
   SET i=i+1;
  END LOOP;
 ELSE
  SET temp = original;
 END IF;
 RETURN temp;
END$$
DELIMITER ;
 
SELECT * FROM  `prueba` WHERE col1 regex_replace('hola\:[a-zA-Z0-9\-]*','','adios');