...
addhandler picturebox2.click, addressof save
end sub
 
private sub save(sender as object,  e as EventArgs)
...
end sub

Public Class Form1
 
    Dim proxyForm As New Form
    Private Sub Form1_Load(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles MyBase.Load
        Me.ControlBox = False
        Me.MinimizeBox = False
        Me.MaximizeBox = False
        Me.Text = ""
        Me.ShowInTaskbar = False
        proxyForm.Text = "MyText"
        proxyForm.Opacity = 0 'make ProxyFrom invisible.
        proxyForm.Show(Me) 'make ProxyForm Owned
    End Sub
End Class