Public Class Form1
    Private Declare Sub mouse_event Lib "user32" (ByVal dwflags As Long, ByVal dx As Long, ByVal dy As Long, ByVal cbuttons As Long, ByVal dwExtraInfo As Long)
    Private Const mouseclickup = 4
    Private Const mouseclickdown = 2
    Private Declare Function GetAsyncKeyState Lib "user32" (ByVal vkey As Long) As Integer

    Private Sub Timer1_Tick(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Timer1.Tick
        Windows.Forms.Cursor.Position = New Point(Windows.Forms.Cursor.Position.X, Windows.Forms.Cursor.Position.Y)
        Timer1.Interval = NumericUpDown1.Value
        Label1.Text = Windows.Forms.Cursor.Position.X
        Label2.Text = Windows.Forms.Cursor.Position.Y
 
        Windows.Forms.Cursor.Position = New Point(TextBox1.Text, TextBox2.Text)
 
        mouse_event(mouseclickdown, 0, 0, 0, 0)
        mouse_event(mouseclickup, 0, 0, 0, 0)
 
        Windows.Forms.Cursor.Position = New Point(Label1.Text, Label2.Text)
    End Sub
 

 Private Sub Timer2_Tick(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Timer2.Tick
        Dim hotkey As Boolean
        hotkey = GetAsyncKeyState(Keys.F9)
        If hotkey = True Then timer1.start()
        Dim hotkey1 As Boolean
        hotkey1 = GetAsyncKeyState(Keys.F10)
        If hotkey1 = True Then Timer1.Stop()
    End Sub

    Private Sub Timer3_Tick(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Timer3.Tick
 Dim Posicion As Boolean
        Posicion = GetAsyncKeyState(Keys.F7) 
        If Posicion = True Then
            TextBox1.Text = MousePosition.X : TextBox2.Text = MousePosition.Y
        End If
        If Posicion = False Then
        End if
    End Sub
End Class

 Imports System.Timers
Dim nPicoSeg As Integer = 5
Dim tim1 As Timer = New Timer(nPicoSeg * 10 ^ (-9))

Public Class Form1
    Private Declare Sub mouse_event Lib "user32" (ByVal dwflags As Long, ByVal dx As Long, ByVal dy As Long, ByVal cbuttons As Long, ByVal dwExtraInfo As Long)
    Private Const mouseclickup = 4
    Private Const mouseclickdown = 2
    Private Declare Function GetAsyncKeyState Lib "user32" (ByVal vkey As Long) As Integer
    Declare Function GetTickCount Lib "kernel32" Alias "GetTickCount" () As Long
 
    Private Sub Button1_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Button1.Click
        Timer1.Start()
    End Sub
 
    Private Sub Button2_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Button2.Click
        Timer1.Stop()
    End Sub
 
    Private Sub Timer1_Tick(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Timer1.Tick
        Windows.Forms.Cursor.Position = New Point(TextBox1.Text, TextBox2.Text)
        mouse_event(mouseclickdown, 3, 7, 1, 2)
        mouse_event(mouseclickup, 2, 5, 9, 3)
 
    End Sub
    Private Sub Timer2_Tick(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Timer2.Tick
        Dim hotkey As Boolean
        hotkey = GetAsyncKeyState(Keys.F3)
        If hotkey = True Then Timer1.Start()
        Dim hotkey1 As Boolean
        hotkey1 = GetAsyncKeyState(Keys.F4)
        If hotkey1 = True Then Timer1.Stop()
    End Sub
 
    Private Sub Timer3_Tick(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Timer3.Tick, Timer4.Tick
        Label1.Text = Cursor.Position.X
        Label2.Text = Cursor.Position.Y
    End Sub
 
    Private Sub RadioButton1_CheckedChanged(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles RadioButton1.CheckedChanged
        Timer1.Interval = (1)
    End Sub
 
    Private Sub NumericUpDown1_ValueChanged(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles NumericUpDown1.ValueChanged
        Timer1.Interval = NumericUpDown1.Value
    End Sub
 
    Private Sub NumericUpDown2_ValueChanged(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles NumericUpDown2.ValueChanged
        Timer1.Interval = NumericUpDown2.Value
    End Sub
End Class
Private Sub esperar(ByVal espera As Long)
    Dim inicio As Long
    Dim fin As Long
    inicio = GetTickCount()
    fin = inicio + espera 'espera es el tiempo del contador en milisec
    While fin > GetTickCount
        DoEvents()
    End While
End Sub